The Extracellular Matrix Glycoprotein Elastin Microfibril Interface Located Protein 2: A Dual Role in the Tumor Microenvironment

We have recently reported that elastin microfibril interface located protein 2 (EMILIN2), an extracellular matrix (ECM) glycoprotein, triggers cell death through a direct binding to death receptors. EMILIN2 thus influences cell viability through a mechanism that is unique for an ECM molecule. In th...

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Bibliographic Details
Main Authors: Maurizio Mongiat, Stefano Marastoni, Giovanni Ligresti, Erica Lorenzon, Monica Schiappacassi, Roberto Perris, Sergio Frustaci, Alfonso Colombatti
Format: Article
Language:English
Published: Elsevier 2010-04-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558610800089