The ensemble diversity of non-coding RNA structure is lower than random sequence

In addition to energetically optimal structures, RNAs can fold into near energy suboptimal conformations that may be populated and play functional roles. The diversity of this structural ensemble can be estimated using a metric derived from the calculated RNA partition function: the ensemble diversi...

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Bibliographic Details
Main Author: Walter N. Moss
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2018-09-01
Series:Non-coding RNA Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2468054018300271