The ensemble diversity of non-coding RNA structure is lower than random sequence
In addition to energetically optimal structures, RNAs can fold into near energy suboptimal conformations that may be populated and play functional roles. The diversity of this structural ensemble can be estimated using a metric derived from the calculated RNA partition function: the ensemble diversi...
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Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2018-09-01
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Series: | Non-coding RNA Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2468054018300271 |