Genome mining and UHPLC–QTOF–MS/MS to identify the potential antimicrobial compounds and determine the specificity of biosynthetic gene clusters in Bacillus subtilis NCD-2

Genome mining and UHPLC–QTOF–MS/MS to identify the potential antimicrobial compounds and determine the specificity of biosynthetic gene clusters in Bacillus subtilis NCD-2

Abstract Background Bacillus subtilis strain NCD-2 is an excellent biocontrol agent against plant soil-borne diseases and shows broad-spectrum antifungal activities. This study aimed to explore some secondary metabolite biosynthetic gene clusters and related antimicrobial compounds in strain NCD-2....

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Bibliographic Details
Main Authors: Zhenhe Su, Xiuye Chen, Xiaomeng Liu, Qinggang Guo, Shezeng Li, Xiuyun Lu, Xiaoyun Zhang, Peipei Wang, Lihong Dong, Weisong Zhao, Ping Ma
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Genomics
Subjects:
Bacillus subtilis NCD-2
Genome mining
UHPLC–QTOF–MS/MS
Secondary metabolites
Fengycin
Online Access:http://link.springer.com/article/10.1186/s12864-020-07160-2

Internet

http://link.springer.com/article/10.1186/s12864-020-07160-2

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