CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes.

CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes.

Histones constitute a type of essential nuclear proteins important for chromatin structure and functions. The expression of major histones is strictly confined to the S phase of a cell cycle and tightly coupled to DNA replication.With RT-qPCR and ChIP assays, we investigated transcriptional regulati...

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Bibliographic Details
Main Authors: Hongpeng He, Fa-Xing Yu, Chi Sun, Yan Luo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3137613?pdf=render

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