CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes.
Histones constitute a type of essential nuclear proteins important for chromatin structure and functions. The expression of major histones is strictly confined to the S phase of a cell cycle and tightly coupled to DNA replication.With RT-qPCR and ChIP assays, we investigated transcriptional regulati...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3137613?pdf=render |