Polyplexes of Functional PAMAM Dendrimer/Apoptin Gene Induce Apoptosis of Human Primary Glioma Cells In Vitro

Polyplexes of Functional PAMAM Dendrimer/Apoptin Gene Induce Apoptosis of Human Primary Glioma Cells In Vitro

Highly efficient and safe gene delivery has become an important aspect of neuronal gene therapy. We evaluated the ability of polyamidoamine (PAMAM) dendrimer grafted with phenylalanine, histidine, and arginine (PAMAM-FHR), a nonviral gene delivery vector, to deliver a therapeutic, tumor cell-specifi...

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Bibliographic Details
Main Authors: Yoonhee Bae, Le Thi Thuy, Young Hwa Lee, Kyung Soo Ko, Jin Han, Joon Sig Choi
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Polymers
Subjects:
PAMAM-FHR
apoptin
apoptosis
cancer therapy
Online Access:https://www.mdpi.com/2073-4360/11/2/296

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https://www.mdpi.com/2073-4360/11/2/296

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