Definitive hematopoietic stem cells minimally contribute to embryonic hematopoiesis

Summary: Hematopoietic stem cells (HSCs) are rare cells that arise in the embryo and sustain adult hematopoiesis. Although the functional potential of nascent HSCs is detectable by transplantation, their native contribution during development is unknown, in part due to the overlapping genesis and ma...

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Bibliographic Details
Main Authors: Bianca A. Ulloa, Samima S. Habbsa, Kathryn S. Potts, Alana Lewis, Mia McKinstry, Sara G. Payne, Julio C. Flores, Anastasia Nizhnik, Maria Feliz Norberto, Christian Mosimann, Teresa V. Bowman
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721011505