The extent of damage following repeated injury to cultured hippocampal cells is dependent on the severity of insult and inter-injury interval

Recent evidence suggests repeated mild brain trauma may result in cumulative damage. We investigated cell damage and death in hippocampal cultures following repeated mechanical trauma in vitro by measuring propidium iodide (PrI) uptake, release of neuron-specific enolase (NSE) and glial S-100β prote...

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Bibliographic Details
Main Authors: Jennifer E. Slemmer, John T. Weber
Format: Article
Language:English
Published: Elsevier 2005-04-01
Series:Neurobiology of Disease
Subjects:
NSE
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104002335