Sensitivity of EGFR/HER-2 Positive Cells Isolated from Ascitic Fluid of Advanced Ovarian Cancer Patients to EGFR/HER-2 Inhibitors

Sensitivity of EGFR/HER-2 Positive Cells Isolated from Ascitic Fluid of Advanced Ovarian Cancer Patients to EGFR/HER-2 Inhibitors

Background: advanced ovarian cancer often presents with ascites. These ascites contain small clusters of cancer cells, which may contribute greatly to the metastatic potential of ovarian cancer in the peritoneal cavity. Therefore, understanding the unique protein expressions of this cell population...

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Bibliographic Details
Main Authors: Kenny Chitcholtan, Dianne Harker, Bryony Simcock, Peter Sykes
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Applied Sciences
Subjects:
ovarian cancer
cell clusters
EGFR
HER-2
gefitinib
canertinib
Online Access:https://www.mdpi.com/2076-3417/10/7/2343

Internet

https://www.mdpi.com/2076-3417/10/7/2343

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