Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection

Tcf1+ cells are required to maintain the inflationary T cell pool upon MCMV infection

Upon infection with cytomegalovirus, CD8+ T cells undergo prolific expansion in a process known as memory inflation. Here the authors define a population of Tcf1 expressing cells within the inflationary pool that is critical in fuelling this process.

Bibliographic Details
Main Authors: Suzanne P. M. Welten, Alexander Yermanos, Nicolas S. Baumann, Franziska Wagen, Nathalie Oetiker, Ioana Sandu, Alessandro Pedrioli, Jennifer D. Oduro, Sai T. Reddy, Luka Cicin-Sain, Werner Held, Annette Oxenius
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16219-3

Internet

https://doi.org/10.1038/s41467-020-16219-3

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