Chromosome copy number changes carry prognostic information independent of KIT/PDGFRA point mutations in gastrointestinal stromal tumors

Chromosome copy number changes carry prognostic information independent of KIT/PDGFRA point mutations in gastrointestinal stromal tumors

<p>Abstract</p> <p>Background</p> <p>Oncogenic point mutations in <it>KIT </it>or <it>PDGFRA </it>are recognized as the primary events responsible for the pathogenesis of most gastrointestinal stromal tumors (GIST), but additional genomic alterat...

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Bibliographic Details
Main Authors: Lopes Paula, Santos Lúcio, Dinis José, Soares Marta, Santos Catarina, Mesquita Bárbara, Pinheiro Manuela, Pinto Carla, Vieira Joana, Ribeiro Franclim R, Veiga Isabel, Silva Mara, Afonso Mariana, Lopes Carlos, Teixeira Manuel R
Format: Article
Language:English
Published: BMC 2010-05-01
Series:BMC Medicine
Online Access:http://www.biomedcentral.com/1741-7015/8/26

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http://www.biomedcentral.com/1741-7015/8/26

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