Development and regulation of chloride homeostasis in the central nervous system
GABA (γ-aminobutyric acid) is the main inhibitory neurotransmitter of the mature central nervous system. The developmental switch of GABAergic transmission from excitation to inhibition is induced by changes in Cl- gradients, which are generated by cation-Cl- co-transporters. An accumulation of Cl-...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2015-09-01
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| Series: | Frontiers in Cellular Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00371/full |