Conformational Plasticity of the Active Site Entrance in <i>E. coli</i> Aspartate Transcarbamoylase and Its Implication in Feedback Regulation
Aspartate transcarbamoylase (ATCase) has been studied for decades and <i>Escherichia coli</i> ATCase is referred as a “textbook example” for both feedback regulation and cooperativity. However, several critical questions about the catalytic and regulatory mechanisms o...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-01-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/21/1/320 |