The role of FLT3 inhibitors as maintenance therapy following hematopoietic stem cell transplant

Activating mutations in FLT3 in acute myeloid leukemia (AML) portend a poor prognosis, and targeting FLT3 with a tyrosine kinase inhibitor has been an area of intense research recently. Most FLT3 mutated AML patients undergo hematopoietic stem cell transplantation (HSCT) as standard of care but a si...

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Bibliographic Details
Main Authors: Grace Xiuqing Li, Lan Wang, Bassam Yaghmour, Giridharan Ramsingh, George Yaghmour
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Leukemia Research Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213048918300499