Synthesis, Structural Studies and Biological Evaluation of Connections of Thiosemicarbazide, 1,2,4-Triazole and 1,3,4-Thiadiazole with Palmitic Acid

Synthesis, Structural Studies and Biological Evaluation of Connections of Thiosemicarbazide, 1,2,4-Triazole and 1,3,4-Thiadiazole with Palmitic Acid

Thirty new derivatives of palmitic acid were efficiently synthesized. All obtained compounds can be divided into three groups of derivatives: Thiosemicarbazides (compounds 1–10), 1,2,4-triazoles (compounds 1a–10a) and 1,3,4-thiadiazoles (compounds 1b–10b) moieties. 1H-NMR, 13C-NMR and MS methods wer...

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Bibliographic Details
Main Authors: Michał Jóźwiak, Karolina Stępień, Małgorzata Wrzosek, Wioletta Olejarz, Grażyna Kubiak-Tomaszewska, Anna Filipowska, Wojciech Filipowski, Marta Struga
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Molecules
Subjects:
palmitic acid derivatives
thiosemicarbazides
1,2,4-triazoles
1,3,4-thiadiazoles
antimicrobial activity
quantitative structure-activity relationship
Online Access:http://www.mdpi.com/1420-3049/23/4/822

Internet

http://www.mdpi.com/1420-3049/23/4/822

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