MicroRNA-370 protects against myocardial ischemia/reperfusion injury in mice following sevoflurane anesthetic preconditioning through PLIN5-dependent PPAR signaling pathway

MicroRNA-370 protects against myocardial ischemia/reperfusion injury in mice following sevoflurane anesthetic preconditioning through PLIN5-dependent PPAR signaling pathway

Myocardial ischemia/reperfusion injury (IRI) has long been identified to be a contributor to adverse cardiovascular outcomes following myocardial ischemia, cardiac surgery or circulatory arrest. This study aims to investigate the effects of microRNA (miR-370) targeting perilipin-5 (PLIN5) in mice fo...

Full description

Bibliographic Details
Main Authors: Yan-Bin Zhao, Juan Zhao, Li-Jun Zhang, Run-Gang Shan, Zhen-Zhong Sun, Kai Wang, Jin-Quan Chen, Ji-Xue Mu
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
MicroRNA-370
Perilipin-5
Peroxisome proliferator activated-receptor signaling pathway
Myocardial ischemia/reperfusion injury
Sevoflurane
Preconditioning
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218360049

Internet

http://www.sciencedirect.com/science/article/pii/S0753332218360049

Similar Items