Induced hypernatremia in patients with moderate-to-severe ARDS: a randomized controlled study
Abstract Background Induced hypernatremia and hyperosmolarity is protective in animal models of lung injury. We hypothesized that increasing and maintaining plasma sodium between 145 and 150 mmol/l in patients with moderate-to-severe ARDS would be safe and will reduce lung injury. This was a prospec...
Main Authors: | Shailesh Bihari, Shivesh Prakash, Dani L. Dixon, Elena Cavallaro, Andrew D. Bersten |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2021-07-01
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Series: | Intensive Care Medicine Experimental |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40635-021-00399-3 |
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