Induced hypernatremia in patients with moderate-to-severe ARDS: a randomized controlled study

Induced hypernatremia in patients with moderate-to-severe ARDS: a randomized controlled study

Abstract Background Induced hypernatremia and hyperosmolarity is protective in animal models of lung injury. We hypothesized that increasing and maintaining plasma sodium between 145 and 150 mmol/l in patients with moderate-to-severe ARDS would be safe and will reduce lung injury. This was a prospec...

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Bibliographic Details
Main Authors: Shailesh Bihari, Shivesh Prakash, Dani L. Dixon, Elena Cavallaro, Andrew D. Bersten
Format: Article
Language:English
Published: SpringerOpen 2021-07-01
Series:Intensive Care Medicine Experimental
Subjects:
ARDS
Hypernatremia
Hyperosmolarity
Lung injury score
Mechanical Ventilation
Randomized control study
Online Access:https://doi.org/10.1186/s40635-021-00399-3

Internet

https://doi.org/10.1186/s40635-021-00399-3

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