A fln-2 mutation affects lethal pathology and lifespan in C. elegans

C. elegans is a commonly used model organism in the study of ageing, and differences in genetic background can result in varying strain longevity. Here the authors demonstrate that a background mutation in fln-2 affects life-limiting pharyngeal infection and that in the mutant background the benefic...

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Bibliographic Details
Main Authors: Yuan Zhao, Hongyuan Wang, Richard J. Poole, David Gems
Format: Article
Language:English
Published: Nature Publishing Group 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13062-z