Toll-like receptor 7 stimulates the expression of Epstein-Barr virus latent membrane protein 1.

Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus. Toll-like receptor 7 (TLR7) is involved in host innate immunity against pathogens, and its aberrant activation is linked to the development of systemic lupus erythematosus (SLE, also called "lupus"). Type I interferons (IFN) are a...

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Bibliographic Details
Main Authors: Robert M Valente, Erica Ehlers, Dongsheng Xu, Humera Ahmad, Andrew Steadman, Laura Blasnitz, You Zhou, Lisa Kastanek, Bin Meng, Luwen Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3432040?pdf=render