Possible roles of mechanical cell elimination intrinsic to growing tissues from the perspective of tissue growth efficiency and homeostasis.

Cell competition is a phenomenon originally described as the competition between cell populations with different genetic backgrounds; losing cells with lower fitness are eliminated. With the progress in identification of related molecules, some reports described the relevance of cell mechanics durin...

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Bibliographic Details
Main Authors: Sang-Woo Lee, Yoshihiro Morishita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5547694?pdf=render