Evolutionary diversification of the trypanosome haptoglobin-haemoglobin receptor from an ancestral haemoglobin receptor

The haptoglobin-haemoglobin receptor of the African trypanosome species, Trypanosoma brucei, is expressed when the parasite is in the bloodstream of the mammalian host, allowing it to acquire haem through the uptake of haptoglobin-haemoglobin complexes. Here we show that in Trypanosoma congolense th...

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Bibliographic Details
Main Authors: Harriet Lane-Serff, Paula MacGregor, Lori Peacock, Olivia JS Macleod, Christopher Kay, Wendy Gibson, Matthew K Higgins, Mark Carrington
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/13044