Cancer and chemotherapy contribute to muscle loss by activating common signaling pathways

Cachexia represents one of the primary complications of colorectal cancer due to its effects on depletion of muscle and fat. Evidence suggests that chemotherapeutic regimens, such as Folfiri, contribute to cachexia-related symptoms. The purpose of the present study was to investigate the cachexia si...

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Bibliographic Details
Main Authors: Rafael Barreto, Giorgia Mandili, Frank A Witzmann, Francesco Novelli, Teresa A Zimmers, Andrea Bonetto
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00472/full