Glycosylated Notch and Cancer

Glycosylated Notch and Cancer

Glycosylation is one of the key components influencing several signaling pathways implicated in cell survival and growth. The Notch signaling pathway plays a pivotal role in numerous cell fate specifications during metazoan development. Both Notch and its ligands are repeatedly glycosylated by the a...

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Bibliographic Details
Main Authors: Shanmugasundaram ePakkiriswami, Africa eCouto, Usha eNagarajan, Marios eGeorgiou
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Oncology
Subjects:
Epidermal Growth Factor
Glycosyltransferases
Cancer
tumorigenesis
Notch signaling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00037/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00037/full

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