Activation of SphK1 by adipocytes mediates epithelial ovarian cancer cell proliferation

Activation of SphK1 by adipocytes mediates epithelial ovarian cancer cell proliferation

Abstract Background Adipocytes, active facilitators of epithelial ovarian cancer (EOC) growth, have been implicated in the link between obesity and EOC. However, the current understanding of the mechanisms underlying adipocyte-induced EOC cell proliferation remains incomplete. Results We provide the...

Full description

Bibliographic Details
Main Authors: Lan Dai, Chen Wang, Keqi Song, Wenjing Wang, Wen Di
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Journal of Ovarian Research
Subjects:
Epithelial ovarian cancer (EOC)
Adipocytes
Sphingosine kinase 1 (SphK1)
Sphingosine 1-phosphate receptor (S1PR)
Proliferation
Online Access:https://doi.org/10.1186/s13048-021-00815-y

Internet

https://doi.org/10.1186/s13048-021-00815-y

Similar Items