Angiotensin II receptor 1 antibodies associate with post-transplant focal segmental glomerulosclerosis and proteinuria

Angiotensin II receptor 1 antibodies associate with post-transplant focal segmental glomerulosclerosis and proteinuria

Abstract Background Angiotensin II type 1 receptors (AT1Rs) are expressed on podocytes, endothelial and other cells, and play an essential role in the maintenance of podocyte function and vascular homeostasis. The presence of AT1R antibodies (AT1R-Abs) leads to activation of these receptors resultin...

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Bibliographic Details
Main Authors: Mohammad Abuzeineh, Amtul Aala, Sami Alasfar, Nada Alachkar
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Nephrology
Subjects:
Angiotensin II type 1 receptors (AT1R) antibody
Kidney transplant
Focal segmental Glomerulosclerosis
Proteinuria
Online Access:http://link.springer.com/article/10.1186/s12882-020-01910-w

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http://link.springer.com/article/10.1186/s12882-020-01910-w

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