Pathological Consequences of Hepatic mTORC1 Dysregulation

The mammalian target of rapamycin complex 1 (mTORC1) is a central regulator of metabolism that integrates environmental inputs, including nutrients, growth factors, and stress signals. mTORC1 activation upregulates anabolism of diverse macromolecules, such as proteins, lipids, and nucleic acids, whi...

Full description

Bibliographic Details
Main Authors: Chun-Seok Cho, Allison Ho Kowalsky, Jun Hee Lee
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/8/896