Enhanced Radiosensitization for Cancer Treatment with Gold Nanoparticles through Sonoporation

Enhanced Radiosensitization for Cancer Treatment with Gold Nanoparticles through Sonoporation

<b> </b>We demonstrate the megavoltage (MV) radiosensitization of a human liver cancer line by combining gold-nanoparticle-encapsulated microbubbles (AuMBs) with ultrasound. Microbubbles-mediated sonoporation was administered for 5 min, at 2 h prior to applying radiotherapy. The intracel...

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Bibliographic Details
Main Authors: Shao-Lun Lu, Wei-Wen Liu, Jason Chia-Hsien Cheng, Lien-Chieh Lin, Churng-Ren Chris Wang, Pai-Chi Li
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
sonoporation
microbubbles
gold nanoparticles
cavitation
radiotherapy
radiosensitization
Online Access:https://www.mdpi.com/1422-0067/21/21/8370

Internet

https://www.mdpi.com/1422-0067/21/21/8370

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