Frequent amplification of CENPF, GMNN and CDK13 genes in hepatocellular carcinomas.

Frequent amplification of CENPF, GMNN and CDK13 genes in hepatocellular carcinomas.

Genomic changes frequently occur in cancer cells during tumorigenesis from normal cells. Using the Illumina Human NS-12 single-nucleotide polymorphism (SNP) chip to screen for gene copy number changes in primary hepatocellular carcinomas (HCCs), we initially detected amplification of 35 genes from f...

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Main Authors: Hye-Eun Kim, Dae-Ghon Kim, Kyung Jin Lee, Jang Geun Son, Min-Young Song, Young-Mi Park, Jae-Jung Kim, Sung-Won Cho, Sung-Gil Chi, Hyun Sub Cheong, Hyoung Doo Shin, Sang-Wook Lee, Jong-Keuk Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3418236?pdf=render

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