Frequent amplification of CENPF, GMNN and CDK13 genes in hepatocellular carcinomas.

Genomic changes frequently occur in cancer cells during tumorigenesis from normal cells. Using the Illumina Human NS-12 single-nucleotide polymorphism (SNP) chip to screen for gene copy number changes in primary hepatocellular carcinomas (HCCs), we initially detected amplification of 35 genes from f...

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Main Authors: Hye-Eun Kim, Dae-Ghon Kim, Kyung Jin Lee, Jang Geun Son, Min-Young Song, Young-Mi Park, Jae-Jung Kim, Sung-Won Cho, Sung-Gil Chi, Hyun Sub Cheong, Hyoung Doo Shin, Sang-Wook Lee, Jong-Keuk Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3418236?pdf=render