Analysis of the prevalence, secretion and function of a cell cycle-inhibiting factor in the melioidosis pathogen Burkholderia pseudomallei.

Enteropathogenic and enterohaemorrhagic Escherichia coli express a cell cycle-inhibiting factor (Cif), that is injected into host cells via a Type III secretion system (T3SS) leading to arrest of cell division, delayed apoptosis and cytoskeletal rearrangements. A homologue of Cif has been identified...

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Main Authors: Pornpan Pumirat, Charles Vander Broek, Niramol Juntawieng, Veerachat Muangsombut, Pattarachai Kiratisin, Kovit Pattanapanyasat, Joanne M Stevens, Mark P Stevens, Sunee Korbsrisate
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4014488?pdf=render