High-dimensional mediation analysis in survival models.

Mediation analysis with high-dimensional DNA methylation markers is important in identifying epigenetic pathways between environmental exposures and health outcomes. There have been some methodology developments of mediation analysis with high-dimensional mediators. However, high-dimensional mediati...

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Bibliographic Details
Main Authors: Chengwen Luo, Botao Fa, Yuting Yan, Yang Wang, Yiwang Zhou, Yue Zhang, Zhangsheng Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-04-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007768