Obesity-Associated MiR-342-3p Promotes Adipogenesis of Mesenchymal Stem Cells by Suppressing CtBP2 and Releasing C/EBPα from CtBP2 Binding

Obesity-Associated MiR-342-3p Promotes Adipogenesis of Mesenchymal Stem Cells by Suppressing CtBP2 and Releasing C/EBPα from CtBP2 Binding

Background/Aims: The elucidation of the molecular mechanism of adipocyte differentiation in mesenchymal stem cells is of essential importance for the development of treatments for metabolic diseases, such as obesity and diabetes. Methods: The expression levels of miR-342-3p and carboxy-terminal bind...

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Bibliographic Details
Main Authors: Liang Wang, Lei Xu, Min Xu, Guoqiang Liu, Jian Xing, Caifeng Sun, Huifang Ding
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
CtBP2
Mesenchymal stem cells
miR-342-3p
Obesity
Adipogenic differentiation
Online Access:http://www.karger.com/Article/FullText/374032

Internet

http://www.karger.com/Article/FullText/374032

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