Early Life Adversity Alters the Developmental Profiles of Addiction-Related Prefrontal Cortex Circuitry

Early adverse experience is a well-known risk factor for addictive behaviors later in life. Drug addiction typically manifests during adolescence in parallel with the later-developing prefrontal cortex (PFC). While it has been shown that dopaminergic modulation within the PFC is involved in addictio...

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Bibliographic Details
Main Authors: Susan L. Andersen, Heather C. Brenhouse, Jodi L. Lukkes
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:Brain Sciences
Subjects:
Online Access:http://www.mdpi.com/2076-3425/3/1/143