Rapid modulation of synaptogenesis and spinogenesis by 17β-estradiol in primary cortical neurons

Rapid modulation of synaptogenesis and spinogenesis by 17β-estradiol in primary cortical neurons

In the mammalian forebrain, the majority of excitatory synapses occur on dendritic spines. Changes in the number of these structures is important for brain development, plasticity and the refinement of neuronal circuits. The formation of excitatory synapses involves the coordinated formation of dend...

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Bibliographic Details
Main Authors: Katherine J Sellers, Filippo eErli, Pooja eRaval, Iain A Watson, Ding eCheng, Deepak Prakash Srivastava
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Dendritic Spines
Akt
estrogen receptor
PSD-95
neuroligin-1
ERK1/2
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00137/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00137/full

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