Removal of AU bias from microarray mRNA expression data enhances computational identification of active microRNAs.

Elucidation of regulatory roles played by microRNAs (miRs) in various biological networks is one of the greatest challenges of present molecular and computational biology. The integrated analysis of gene expression data and 3'-UTR sequences holds great promise for being an effective means to sy...

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Bibliographic Details
Main Authors: Ran Elkon, Reuven Agami
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-10-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18833292/pdf/?tool=EBI