The influence of conjugation variables on the design and immunogenicity of a glycoconjugate vaccine against Salmonella Typhi.

In recent years there have been major efforts to develop glycoconjugate vaccines based on the Vi polysaccharide that will protect against Salmonella enterica Typhi infections, particularly typhoid fever, which remains a major public health concern in low-income countries. The design of glycoconjugat...

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Bibliographic Details
Main Authors: M Arcuri, R Di Benedetto, A F Cunningham, A Saul, C A MacLennan, F Micoli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0189100