HapCHAT: adaptive haplotype assembly for efficiently leveraging high coverage in long reads

HapCHAT: adaptive haplotype assembly for efficiently leveraging high coverage in long reads

Abstract Background Haplotype assembly is the process of assigning the different alleles of the variants covered by mapped sequencing reads to the two haplotypes of the genome of a human individual. Long reads, which are nowadays cheaper to produce and more widely available than ever before, have be...

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Bibliographic Details
Main Authors: Stefano Beretta, Murray D. Patterson, Simone Zaccaria, Gianluca Della Vedova, Paola Bonizzoni
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Bioinformatics
Subjects:
Single individual haplotyping
Long reads
High coverage
Haplotype assembly
Minimum error correction
Online Access:http://link.springer.com/article/10.1186/s12859-018-2253-8

Internet

http://link.springer.com/article/10.1186/s12859-018-2253-8

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