Characterization of Bovine Induced Pluripotent Stem Cells by Lentiviral Transduction of Reprogramming Factor Fusion Proteins

<p>Pluripotent stem cells from domesticated animals have potential applications in transgenic breeding. Here, we describe induced pluripotent stem (iPS) cells derived from bovine fetal fibroblasts by lentiviral transduction of Oct4, Sox2, Klf4 and c-Myc defined-factor fusion proteins. Bovine i...

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Bibliographic Details
Main Author: Hongguo Cao, Pan Yang, Yong Pu, Xueping Sun, Huiqun Yin, Yu Zhang, Yunhai Zhang, Yunsheng Li, Ya Liu, Fugui Fang, Zijun Zhang, Yong Tao, Xiaorong Zhang
Format: Article
Language:English
Published: Ivyspring International Publisher 2012-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v08p0498.htm