Bile acid binding resin improves metabolic control through the induction of energy expenditure.

Bile acid binding resin improves metabolic control through the induction of energy expenditure.

BACKGROUND: Besides well-established roles of bile acids (BA) in dietary lipid absorption and cholesterol homeostasis, it has recently become clear that BA is also a biological signaling molecule. We have shown that strategies aimed at activating TGR5 by increasing the BA pool size with BA administr...

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Bibliographic Details
Main Authors: Mitsuhiro Watanabe, Kohkichi Morimoto, Sander M Houten, Nao Kaneko-Iwasaki, Taichi Sugizaki, Yasushi Horai, Chikage Mataki, Hiroyuki Sato, Karin Murahashi, Eri Arita, Kristina Schoonjans, Tatsuya Suzuki, Hiroshi Itoh, Johan Auwerx
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3430641?pdf=render

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http://europepmc.org/articles/PMC3430641?pdf=render

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