Full cyclic coordinate descent: solving the protein loop closure problem in C<it>α </it>space

<p>Abstract</p> <p>Background</p> <p>Various forms of the so-called <it>loop closure problem </it>are crucial to protein structure prediction methods. Given an N- and a C-terminal end, the problem consists of finding a suitable segment of a certain length th...

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Bibliographic Details
Main Authors: Hamelryck Thomas, Boomsma Wouter
Format: Article
Language:English
Published: BMC 2005-06-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/6/159