Mesenchymal Stromal Cell-Derived Extracellular Vesicles Protect Against Acute Kidney Injury Through Anti-Oxidation by Enhancing Nrf2/ARE Activation in Rats

Background/Aims: Anti-oxidation is an effective strategy for curing acute kidney injury (AKI). Herein, we suggest that extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) might play an anti-oxidative role by enhancing Nrf2/ARE activation in AKI. Methods: EVs isolated from the...

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Bibliographic Details
Main Authors: Guangyuan Zhang, Xiangyu Zou, Yeqing Huang, Feng Wang, Shuai Miao, Guohua Liu, Ming Chen, Yingjian Zhu
Format: Article
Language:English
Published: Karger Publishers 2016-02-01
Series:Kidney & Blood Pressure Research
Subjects:
Online Access:http://www.karger.com/Article/FullText/443413