Pharmacological Inhibitors of the NLRP3 Inflammasome

Inflammasomes play a crucial role in innate immunity by serving as signaling platforms which deal with a plethora of pathogenic products and cellular products associated with stress and damage. By far, the best studied and most characterized inflammasome is NLRP3 inflammasome, which consists of NLRP...

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Bibliographic Details
Main Authors: Ayesha Zahid, Bofeng Li, Arnaud John Kombe Kombe, Tengchuan Jin, Jinhui Tao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02538/full