Mosaic analysis and tumor induction in zebrafish by microsatellite instability-mediated stochastic gene expression

Mosaic analysis, in which two or more populations of cells with differing genotypes are studied in a single animal, is a powerful approach to study developmental mechanisms and gene function in vivo. Over recent years, several genetic methods have been developed to achieve mosaicism in zebrafish, bu...

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Bibliographic Details
Main Authors: Wouter Koole, Marcel Tijsterman
Format: Article
Language:English
Published: The Company of Biologists 2014-07-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/7/7/929