Computational Modeling of Genetic Contributions to Excitability and Neural Coding in Layer V Pyramidal Cells: Applications to Schizophrenia Pathology

Pyramidal cells in layer V of the neocortex are one of the most widely studied neuron types in the mammalian brain. Due to their role as integrators of feedforward and cortical feedback inputs, they are well-positioned to contribute to the symptoms and pathology in mental disorders—such as schizophr...

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Bibliographic Details
Main Authors: Tuomo Mäki-Marttunen, Anna Devor, William A. Phillips, Anders M. Dale, Ole A. Andreassen, Gaute T. Einevoll
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Computational Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fncom.2019.00066/full