TEAD transcription factors are required for normal primary myoblast differentiation in vitro and muscle regeneration in vivo.
The TEAD family of transcription factors (TEAD1-4) bind the MCAT element in the regulatory elements of both growth promoting and myogenic differentiation genes. Defining TEAD transcription factor function in myogenesis has proved elusive due to overlapping expression of family members and their func...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-02-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC5323021?pdf=render |