Comprehensive analysis of lumbar disc degeneration and autophagy-related candidate genes, pathways, and targeting drugs

Abstract Background Lumbar disc degeneration (LDD) is an essential pathological mechanism related to low back pain. Current research on spinal surgery focused on the sophisticated mechanisms involved in LDD, and autophagy was regarded as an essential factor in the pathogenesis. Objectives Our resear...

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Bibliographic Details
Main Authors: Wei-long Xu, Yan Zhao
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-021-02417-2