Live and Let Die: Roles of Autophagy in Cadmium Nephrotoxicity
The transition metal ion cadmium (Cd2+) is a significant environmental contaminant. With a biological half-life of ~20 years, Cd2+ accumulates in the kidney cortex, where it particularly damages proximal tubule (PT) cells and can result in renal fibrosis, failure, or cancer. Because death represents...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2015-04-01
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| Series: | Toxics |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2305-6304/3/2/130 |