DNA demethylation upregulated Nrf2 expression in Alzheimer's disease cellular model

DNA demethylation upregulated Nrf2 expression in Alzheimer's disease cellular model

Nuclear factor erythroid 2-related factor 2 (Nrf2) is an important transcription factor in the defense against oxidative stress. Cumulative evidence has shown that oxidative stress plays a key role in the pathogenesis of Alzheimer's disease (AD). Previous animal and clinical studies had observe...

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Bibliographic Details
Main Authors: Huimin eCao, Li eWang, Beibei eChen, Peng eZheng, Yi eHe, Yubin eDing, Yushuang eDeng, Xi eLu, Xiuming eGuo, Yuping eZhang, Yu eLi, Gang eYu
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
Oxidative Stress
Alzheimer's disease
Nrf2
DNA demethylation
NQO1
Cellular model
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00244/full

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http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00244/full

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