Red wine polyphenol compounds favor neovascularisation through estrogen receptor α-independent mechanism in mice.

Red wine polyphenol compounds (RWPC) exert paradoxical effects depending on the dose on post-ischemic neovascularisation. Low dose RWPC (0.2 mg/kg/day) is pro-angiogenic, whereas high dose (20 mg/kg/day) is anti-angiogenic. We recently reported that the endothelial effect of RWPC is mediated through...

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Bibliographic Details
Main Authors: Matthieu Chalopin, Raffaella Soleti, Tarek Benameur, Angela Tesse, Sébastien Faure, Maria Carmen Martínez, Ramaroson Andriantsitohaina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4192547?pdf=render